Mycobacterium leprae (Murray 3rd Ed pp 323)
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Leprosy is caused my mycobacterium leprae. Clinically divided into lepramatous leprosy and tuberculoid leprosy. Patients with tuberculoid leprosy have strong cellular immunity and a weak antibody mediated response. Like M tuberculosis infections, macrophages are activated, phagocytosis occurs, and bacilli replicate and are cleared. In contrast, lepramatous leprosy – in this we have a strong antibody response and a weak cell mediated response. This is the most infectious form of leprosy.
Category: Microbiology Notes
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