NonNarcotic Analgesics - Acetaminophen
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Acetominophen – Analgesic and antipyretic; not anti-inflammatory.
Toxicology: Dose-dependent, potentially fatal hepatic necrosis. Renal tubular necorsis may also occur. If glutathione stores are depleted by large amounts of metabolites resulting from toxic doses, then hepatic damage ensues. N-Acetylcysteine (Mucomyst) is effective if given less than 24 hrs after ingestion.
Therapeutic use: Antipyresis and mild analgesia.Used for individuals allergic to aspirin, those with gout, hemophilia, or peptic ulcers.
Category: Pharmacology Notes
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