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Causative organism : nematode
Disease, disease manifestations:
- Minute intestinal ulcerations
- Severe pruritus ani, leading to haemorrhage and eczema
- Can produce appendicitis
Life-cycle: stages, forms, diseases caused, intervention points:
- Spindle-shaped worms, males (5mm) and females (13mm)
- Inhabit caecum, appendix, adjoining gut, heads attached to mucosa
- Gravid females detach, migrate out to perianal skin (at night)
- Eggs deposited around anus (up to 11,000);
- female dies Eggs contain larvae, mature in 6 hrs
- infective Reach mouth, larvae released into bowel, moulting en route,
- cycle complete in <>
Transmission and shedding:
- Anus to mouth directly
- Exposure to viable eggs on room furniture, door handles, etc.
- Air-borne from bed linen being aired etc.
Hosts, reservoirs in life-cycle; vectors:
- Furniture, bed linen, ass to mouth via hand vectors
- Only human host
Main drugs in treatment:
- Combantrin, mebendazole, albendazole
Main drugs used in prophylaxis (preventative Rx):
Other information:
- Cosmopolitan, more common n temperate regions
- Common in school chlidren
Category:
Microbiology Notes
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