RENAL TUMOURS – BENIGN (Robbins pp 991)

Benign renal tumours do not have much clinical significance because most are found at autopsy.

Renal papillary adenoma (adenoma)

Morphology: Macroscopic: discrete nodules found in cortex, Microscopically: papillary structures, regular cells free of atypia, look exactly like renal cell adenocarcinoma.

Oncocytoma

This is an epithelial tumour arising from intercalated cells of collecting ducts. An oncocyte is a large epithelial cell, with granular cytoplasm, and abundant mitochondria.

Morphology: Macroscopic: encapsulated tumour, Microscopically: eosinophilic cells with abundant mitochrondria

Angiomyolipoma

This is a tumour consisting of: blood vessels (angio), muscle (myo), fat (lipoma). 25%-50% of tuberous sclerosis patients have this ≫ tuberous sclerosis = lesion in cerebral cortex that causes epilepsy, retardation, skin lesions.

Category: Pathology Notes