Clinical features of trace element deficiency:

Trace Elements Manifestations of Deficiency

Iron Anemia, angular stomatitis, atrophic tongue, koilonychias (spoon nails)

Zinc Facial and extremity rash (pustular, vesicular, bullous, seborrheic, or acneiform), skin ulcers, alopecia, confusion, apathy, depression, dysgeusia, poor wound healing

Manganese In humans: Weight loss, dementia, nausea, vomiting, altered hair color, and hypercholesterolemia; in laboratory animals: ataxia, retarded skeletal growth, decreased reproductive function

Copper Neutropenia, anemia, diarrhea, kinky hair, hypothermia, impaired central nervous system development

Fluoride Deficiency state not recognized

Iodine Symptoms and signs of hypothyroidism

Chromium Glucose intolerance, peripheral neuropathy

Selenium Myositis, cardiomyopathy

Category: Biochemistry Notes