Baclofen (Lioresal)
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You are here: Home » Pharmacology Notes » Baclofen (Lioresal)
Action: CNS acting skeletal muscle relaxant. Depresses monosynaptic-polysynaptic afferent reflex activity at spinal cord level. Relieves spasm caused by upper motor neuron lesion. Effective p.o. (orally).
Uses: multiple sclerosis related spasm. Treat trigeminal neuralgia (tics= facial muscles contracting which effect the quality of life, sleep, etc.; usually in the realm of a neurologist rather than a dentist). Not an analgesic.
Side effects: Transient drowsiness, vertigo, fatique, ataxia (movement disorder), confusion, hypotension.
Category: Pharmacology Notes
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