Types of Vasculitis
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12.11.06
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Disease | Blood vessels affected | Remarks |
Takayasu's disease, (Pulseless disease) | Large | Mainly young women from the far east are affected, resulting in a long disease, treatment is difficult |
Kawasaki disease | Large | Children are affected possibly after an infection. Heart arteries are especially affected. Steroid treatment is harmful. Responds to IVIG |
Polyarteritis nodosa (PAN) | Medium | Rare, but quite well known as it was the earliest vasculitis to be recognised. |
Temporal arteritis (Giant cell arteritis) | Medium | Common disease of over 60's that causes headache and general illness, sometimes with other symptoms. Responds to steroids alone. |
Churg-Strauss syndrome | Medium/Small | Disease of over 50's often with late onset asthma. Particularly affects lung, and nerves to arms and legs. ANCA usually present. |
Microscopic Polyarteritis (MPA) | Small | Affects all ages but more common in elderly. Kidneys, skin and gut affected. ANCA usually present. |
Wegener's granulomatosis | Small | All ages and similar to MPA, but may also cause a slower longer inflammation also affecting nose, sinuses and lungs. ANCA is useful. |
Henoch - Schonlein Purpura | Small | Common in children, who usually get a rash, abdominal pain (gut vasculitis) and mild kidney involvement. Often more severe when it occurs in adults. ANCA negative |
Category: Pathology Notes
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