Types of Vasculitis

on 12.11.06 with 0 comments



Disease

Blood vessels affected

Remarks

Takayasu's disease,
(Pulseless disease)
Large Mainly young women from the far east are affected, resulting in a long disease, treatment is difficult
Kawasaki disease Large Children are affected possibly after an infection. Heart arteries are especially affected. Steroid treatment is harmful. Responds to IVIG
Polyarteritis nodosa (PAN) Medium Rare, but quite well known as it was the earliest vasculitis to be recognised.
Temporal arteritis
(Giant cell arteritis)
Medium Common disease of over 60's that causes headache and general illness, sometimes with other symptoms. Responds to steroids alone.
Churg-Strauss syndrome Medium/Small Disease of over 50's often with late onset asthma. Particularly affects lung, and nerves to arms and legs. ANCA usually present.
Microscopic Polyarteritis (MPA) Small Affects all ages but more common in elderly. Kidneys, skin and gut affected. ANCA usually present.
Wegener's granulomatosis Small All ages and similar to MPA, but may also cause a slower longer inflammation also affecting nose, sinuses and lungs. ANCA is useful.
Henoch - Schonlein Purpura Small Common in children, who usually get a rash, abdominal pain (gut vasculitis) and mild kidney involvement. Often more severe when it occurs in adults. ANCA negative

Category: Pathology Notes

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