Metabolic Alkalosis

on 27.6.06 with 0 comments



  • Generation by gain of HCO3 and maintained by abnormal renal HCO3 absorption.
  • This is almost always secondary to volume contraction (low Cl in urine, responsive to NaCl, maintained at proximal tubule)
    • Vomiting: net loss of H+ and gain of HCO3.
    • Diuretics: ECFV depletion
    • Chronic diarrhea: ECFV depletion
    • Profound hypokalemia
    • Renal failure: if we cannot filter HCO3 we cannot excrete it.
  • Mineralocorticoid excess: increased H secretion, hypokalemia (Na/K exchanger), saline resistant).

Category: Biochemistry Notes

POST COMMENT

0 comments:

Post a Comment