Renal Clearance
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Renal Clearance (RC) – the rate at which the kidney can remove a substance from the blood
RC = U/P X V
concentration of substance in urine (mg/ml)
U/P = - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
concentration of substance in plasma (mg/ml)
V = rate of the formation of urine (ml/minute)
(normal = 1 ml/minute)
Glomerular Filtration Rate = 125 ml/minute; (determined by challenge with “Inulin”)
RC less than125 – reabsorption is occurring
RC > 125 – tubule cells secrete into the urine
Tags: glomerular, filtration
Category: Physiology Notes
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