Chemical Toxicities/Effects
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| Chemical | Effects |
| b mercaptoethanol | Reduces disulfide bonds. |
| 2,4 dinitrophenol (DNP) | Uncouples ATP synthesis from ETC. |
| Acetaminophen | Hepatotoxic. |
| Aflatoxin | |
| Alcohol | FAS (Teratogen). |
| Aniline dye | Transitional cell CA of bladder. |
| Antimyoin | |
| Arsenic | Angiosarcoma of Liver. SCC. |
| Asbestos | Primary Lung CA. Mesothelioma. |
| Benzene | Acute leukemia. Aplastic anemia. AML. |
| Benzidine | Transitional cell CA of bladder. |
| Bungarotoxin (cobra venom) | Ach receptor perturbants. |
| Cadmium | Prostate CA. Lung CA. |
| Carbon tetrachloride | Liver damage. |
| Carboxypeptidase | Carboxy terminus determination of protein structure. |
| Chewing tobacco | Verrucous CA of mouth. |
| Chloramphenicol | Aplastic anemia. Gray baby syndrome. |
| Chromium | |
| Chymotrypsin | Cleaves protein at Phe, Tyr, Trp. |
| CNBr | Cleaves protein at Met. |
| CO | Shifts ODC to left. Inhibits complex IV of ETC blocking ATP synthesis. |
| Cocaine | Teratogen. |
| Cyanide | Inhibits complex IV of ETC blocking ATP synthesis. |
| Cyclophosphamide | Transitional cell CA of bladder. |
| Diabetes | Teratogen. |
| Diethylstilbesterol | Clear cell adenocarcinoma. Teratogen. |
| Edmund's reagent | Amino terminus determination of protein structure. |
| Ellman's Acid | Quantitative determination of amino acids. |
| Ethylene glycol; antifreeze | Oxalate crystals in renal tubules. |
| FDNB | Amino terminus determination of protein structure. |
| Heroin | Teratogen. |
| Iron | Gastritis. Hepatic necrosis. |
| Lead | Microcytic anemia; blocks heme synthesis. |
| Lithium | Teratogen. |
| Methanol; windshield washer fluid | Blindness. |
| Naphtylene | |
| Nickel | |
| Ninhydrin | Detects amino acids (prolineÞyellow). |
| Nitrosamines | Esophageal CA. Gastric CA. |
| Oligomycin | Inhibitor of ATP synthesis from ETC. |
| Oral contraceptives | |
| Phenacetin | Transitional cell CA of bladder. |
| Rotenone | Inhibits complex I of ETC blocking ATP synthesis. |
| Salicylates | Respiratory alkalosis. Metabolic acidosis. |
| Smoke | SCC of lung, oral, esophagus. Transitional cell CA of bladder. Adenocarcinoma of pancreas. Teratogen. |
| Succinyl choline | Ach receptor perturbants. |
| Thalidomide | Teratogen. |
| Thorotrast | Angiosarcoma of Liver. |
| Trypsin | Cleaves protein at Arg, Lys. |
| Uranium | |
| Vinyl chloride | Angiosarcoma of Liver. |
| Warfarin | Teratogen. |
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